Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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4,981 – 4,995 of 5,528 results

4,981

Aobchem 2-Fluoro-3-isopropoxy-5-methylbenzaldehyde | 97% | CAS 2755718-46-6 | C11H13FO2 | 250mg

2-Fluoro-3-isopropoxy-5-methylbenzaldehyde | 97% | CAS 2755718-46-6 | C11H13FO2 | 250mg

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4,982

Aobchem 5-Fluoro-2-isopropoxy-4-methylbenzaldehyde | 97% | CAS 2901095-56-3 | C11H13FO2 | 1g

5-Fluoro-2-isopropoxy-4-methylbenzaldehyde | 97% | CAS 2901095-56-3 | C11H13FO2 | 1g

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4,983

Aobchem 5-Fluoro-2-isopropoxy-4-methylbenzaldehyde | 97% | CAS 2901095-56-3 | C11H13FO2 | 500mg

5-Fluoro-2-isopropoxy-4-methylbenzaldehyde | 97% | CAS 2901095-56-3 | C11H13FO2 | 500mg

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4,984

Aobchem 2-Methylquinoline-6-boronic acid | ≥95% | CAS 1092790-20-9 | C10H10BNO2 | 1g

2-Methylquinoline-6-boronic acid | ≥95% | CAS 1092790-20-9 | C10H10BNO2 | 1g

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4,985

eMolecules 680596-79-6 | 2-{1,4-dioxaspiro[4.5]dec-7-en-8-yl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | Pharmablock | MFCD04115656 | 266.140 | C14H23BO4 | 97.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 10g | 551088346

2-{1,4-dioxaspiro[4.5]dec-7-en-8-yl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | Pharmablock | 680596-79-6 | MFCD04115656 | 266.140 | C14H23BO4 | 97.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 10g | 551088346

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4,986

Medchemexpress LLC SRI 6409-94 | 127697-58-9 | 99.3% | 379.49 | 1 ML

SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. It serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity.

Causes virgin female outbred Syrian golden hamsters to produce deformed offspring in a dose-dependent manner.
Leads to significant reductions in mean fetal body weight and in the numbers of ossified skeletal districts.

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4,987

Medchemexpress LLC Ro 31-9790 | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 1 ML

Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor used in biochemical and cell-based research. It blocks L-selectin shedding and modulates cytokine shedding in immune cells, displaying submicromolar to micromolar potency across different cell types. The compound is provided as a concentrated solution for laboratory assays and requires appropriate storage and handling.

Inhibits L-selectin and TNF-α shedding in immune cells.
Potent activity with IC50 values as low as 0.3 μM.
Supplied as a 10 mM solution in DMSO for ready-to-use dosing.
High purity suitable for research applications.
High DMSO solubility (50 mg/mL) with warming or sonication if needed.
Stable in solvent when stored at -80°C for long-term preservation.

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4,988

eMolecules 680596-79-6 | 1,4-Dioxaspiro[4.5]-7-decene-8-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | MFCD04115656 | 266.140 | C14H23BO4 | 98.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 25g | 444748645

1,4-Dioxaspiro[4.5]-7-decene-8-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | 680596-79-6 | MFCD04115656 | 266.140 | C14H23BO4 | 98.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 25g | 444748645

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4,989

Apexbio Technology LLC R 59-022 93076-89-2 10mg

R 59-022 (CAS 93076-89-2) is a small molecule inhibitor of diacylglycerol kinase (DGK) demonstrating an IC50 of 2 8 M for DGK activity By inhibiting the conversion of 1-oleoyl-2-acetylglycerol to phosphatidic acid R 59-022 modulates diacylglycerol signaling pathways The compound also exhibits antagonistic effects at serotonin (5-HT) receptors and can induce activation of protein kinase C (PKC) In cellular studies R 59-022 enhances thrombin-induced diacylglycerol accumulation in platelets and suppresses phosphatidic acid formation in neutrophils It serves as a valuable tool for investigating DGK-mediated processes and signal transduction mechanisms

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4,990

Apexbio Technology LLC STF 31 724741-75-7 50mg

STF 31 (CAS 724741-75-7) is a small-molecule inhibitor targeting glucose transporter 1 (GLUT1) with an IC50 of 1 M By antagonizing GLUT1 STF 31 disrupts glucose uptake selectively impairing survival in VHL-deficient renal cell carcinoma (RCC) models that depend on enhanced glycolysis In vitro STF 31 exhibits selective cytotoxicity toward VHL-deficient RCC4 cells while exerting minimal effects on RCC4/VHL controls In vivo administration of STF 31 analogs retards tumor growth in VHL-deficient RCC xenografts without notable toxicity in mice STF 31 is utilized in research to investigate GLUT1-mediated metabolic dependencies and therapeutic vulnerabilities in cancer and neuroinflammatory models

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4,991

Apexbio Technology LLC [Ser25] Protein Kinase C (19-31) 136795-05-6 5mg

[Ser25] Protein Kinase C (19-31) (CAS 136795-05-6) is an oligopeptide derived from the pseudosubstrate regulatory domain (amino acids 19-31) of Protein Kinase C alpha (PKC ) modified by substitution of alanine with serine at residue 25 Its sequence is Arg-Phe-Ala-Arg-Lys-Gly-Ser-Leu-Arg-Gln-Lys-Asn-Val with a molecular weight of 1559 82 and molecular formula C67H118N26O17 It acts as a PKC substrate peptide enabling in vitro measurement of kinase enzymatic activity via serine phosphorylation PKC enzymes participate in diverse cellular processes including adhesion transformation cell cycle control and calcium signaling making this peptide an important tool for kinase activity studies and intracellular signaling research

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4,992

Medchemexpress LLC 2-Octyl-4(1H)-quinolone | 80554-60-5 | ≥98.0% | 257.37 | 100 MG

2-Octyl-4(1H)-quinolone, also known as Compound 14, is a quinolinone alkaloid that can be isolated from the plant Ruta graveolens. It is intended for research use only.

It is a natural product derived from Ruta graveolens.
It exhibits antiproliferative activity against human A2780 cells.
The IC50 value for its antiproliferative activity against A2780 cells is 12 μM after 2 days by Alamar blue assay.

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4,993

Medchemexpress LLC Recombinant mouse interleukin-31 (IL-31) | >85.0% | 50 UG

Recombinant mouse interleukin-31 (IL-31) produced in HEK293 cells with a C-terminal His tag, supplied as a 0.22 μm filtered solution in PBS (pH 7.4). The protein is designed for biochemical and cell-based assays, including receptor binding and signaling studies; manufacturer provides activity, purity, and storage data.

Expressed in HEK293 mammalian cells.
C-terminal His tag for detection and purification.
Supplied in PBS (pH 7.4), 0.22 μm filtered.
>85.0% purity by reducing SDS-PAGE.
Approximate molecular weight 17.1 kDa (reducing SDS-PAGE).
Bioactivity: ED50 ≈ 2.916 μg/mL in receptor-binding ELISA.
Store long-term at -80°C; avoid repeated freeze-thaw.

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4,994

Medchemexpress LLC BSJ-03-204 (triTFA) | 99.9% | 1174.97 | 25 MG

BSJ-03-204 triTFA is a PROTAC connected by ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader, with IC50s of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1. This compound does not induce IKZF1/3 degradation and demonstrates anti-cancer activity.

PROTAC connected by ligands for Cereblon and CDK.
Potent and selective Palbociclib-based CDK4/6 dual degrader.
Demonstrates potent anti-proliferative effects on MCL cell lines.
Induces a G1 arrest.
Selectively degrades CDK4/6 in WT cells without affecting IKZF1/3 degradation.
Exhibits anti-cancer activity.

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4,995

Medchemexpress LLC 2-Octyl-4(1H)-quinolone | 80554-60-5 | ≥98.0% | 257.37 | 25 MG

2-Octyl-4(1H)-quinolone (Compound 14) is a quinolinone alkaloid that can be isolated from *Ruta graveolens*. It has antiproliferative activity against human A2780 cells with an IC50 of 12 μM.

Quinolinone alkaloid
Isolated from *Ruta graveolens*
Antiproliferative activity against human A2780 cells

Pricing & Availability

Quinolines and derivatives

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Medchemexpress LLC SRI 6409-94 | 127697-58-9 | 99.3% | 379.49 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ro 31-9790 | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Octyl-4(1H)-quinolone | 80554-60-5 | ≥98.0% | 257.37 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Recombinant mouse interleukin-31 (IL-31) | >85.0% | 50 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BSJ-03-204 (triTFA) | 99.9% | 1174.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Octyl-4(1H)-quinolone | 80554-60-5 | ≥98.0% | 257.37 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More